Amazing Spider-Man #44 - 1/67

Spider-Man battles the Lizard for the second time in the first of a two-parter.



Amazing Spider-Man #45 - 2/67

Spider-Man continues his second battle with the Lizard in the second issue of a two-parter. 



Amazing Spider-Man #46 - 3/67

1st Shocker. Spider-Man goes up against the Shocker for the first time. 



Amazing Spider-Man #47 - 4/67

Spider-Man battles Kraven the Hunter yet again with a huge supporting cast. 


Daredevil #27 - 4/66

Spider-Man joins Daredevil against the Stilt-Man and the Masked Marauder. 

 
Fantastic Four #61 - 4/66

Peter Parker makes a cameo appearance along with Mary Jane. 


Amazing Spider-Man #48 - 5/67

1st Vulture II (Blackie Drago).  Spider-Man battles Vulture II for the first time. 

 
Strange Tales #156 - 5/66

Spider-Man makes a cameo appearance. 

 
Marvel Super-Heroes #14 - 5/66

1st Sorcerer, 1st Synthetic Man. Spider-Man fights the Sorcerer and Synthetic Man for the first (and only time?)

Amazing Spider-Man #49 - 6/67

Spider-Man is teamed-up against by Kraven the Hunter and Vulture II. 


Amazing Spider-Man #50 - 7/66

1st Kingpin. Johnny Carson, Ed McMahon make an appearance. Spider-Man does not yet meet the Kingpin.

Amazing Spider-Man #51 - 8/66

1st Joe Robertson. Spider-Man battles the Kingpin for the first time.

 
X-Men #35 - 8/66

Spider-Man makes a guest appearance in the X-Men's title.


Amazing Spider-Man #52 - 9/66

Death Frederick Foswell. Spider-Man continues his initial battle battles the Kingpin as a supporting cast member dies.




Amazing Spider-Man Annual #4 - 1966

Spider-Man and the Human Torch tackle Mysterio and the Wizard.



 
Amazing Spider-Man #53 - 10/66

A somewhat epic four part storyline begins with Doctor Octopus.



 
Amazing Spider-Man #54 - 11/66

Part two of the four part storyline with Doctor Octopus.



 
Amazing Spider-Man #55 - 12/66

Part three of the four part storyline with Doctor Octopus.