Amazing Spider-Man #32 - 1/66 Spider-Man goes up against the Master Planner who turns out to be none other than Doctor Octopus.
Amazing Spider-Man #33 - 2/66 Spider-Man continues his battle with Doc Ock and this issue includes one of the most memorable scenes in the history of Spider-Man as depicted on the cover.
	Amazing Spider-Man #34 - 3/66 Spider-Man faces off against Kraven the Hunter for the third time. Second time was when Kraven was part of the Sinister Six.
Amazing Spider-Man #35 - 4/66 Spider-Man battles the Molten Man for the second time.
	Amazing Spider-Man #36 - 5/66 1st Looter. Spider-Man battles the Looter (later becomes the Meteor Man) for the first time.
Daredevil #16 & #17 - 5/65 - 6/66 1st Masked Marauder. Spider-Man appears for the first in the pages of Daredevil and joins him in battling the Masked Marauder.
	Amazing Spider-Man #37 - 6/66 1st Norman Osborn, 1st Mendel Stromm (Robot Master/ Gaunt). Spider-Man battles the the Robot Master (Stromm) for the first time as a new character is introduced as the father of Peter's college friend Harry Osborn. Norman would go on to play a much larger role.
Amazing Spider-Man #38 - 7/66 1st "Just A Guy Named" Joe Smith. Spider-Man battles Just A Guy Named Joe for the first time. Joe would later go on to become more of the hero type.
	Amazing Spider-Man #39 - 8/66 Landmark issue in which Spider-Man and the Green Goblin learn each other's identity. The Green Goblin turns out to be Peter's friends father Norman Osborn, wealthy industrialist.
Amazing Spider-Man #40 - 9/66 Spider-Man and the Green Goblin continue their battle. Norman Osborn becomes amnesiac and forgets that he is the Green Goblin. But not for TOO long!
	Amazing Spider-Man #41 - 10/66 1st Rhino. Spider-Man first battles the Rhino.
Amazing Spider-Man Annual #3 - 1966 Spider-Man is tried out by the Avengers and battles the Incredible Hulk. Spider-Man would later become a reserve member of the Avengers much later in his career.
	Amazing Spider-Man #42 - 11/66 1st Mary Jane Watson (Full Appearance). Spider-Man battles the Rhino and John Jameson in an exo-skeleton battlesuit.
Amazing Spider-Man #43 - 12/66 Spider-Man continues his first long battle with the Rhino. Peter has his first long interaction with Mary Jane Watson.
	Uncanny X-Men #27 - 12/65 Spider-Man makes a one-page appearance in this issue as the Beast and Iceman try to recruit him.